Differential function of the two Atg4 homologues in the aggrephagy pathway in C. elegans
نویسندگان
چکیده
Fan Wu, Yuping Li, Fuxin Wang, Nobuo N. Noda and Hong Zhang Graduate Program in Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, P.R. China State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, P.R.China National Institute of Biological Sciences, Beijing, 102206, P.R. China Institute of Microbial Chemistry, Tokyo, Tokyo 141-0021, Japan
منابع مشابه
Differential function of the two Atg4 homologues in the aggrephagy pathway in Caenorhabditis elegans.
The presence of multiple homologues of the same yeast Atg protein endows an additional layer of complexity on the autophagy pathway in higher eukaryotes. The physiological function of the individual genes, however, remains largely unknown. Here we investigated the role of the two Caenorhabditis elegans homologues of the cysteine protease Atg4 in the pathway responsible for degradation of protei...
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